PixelFlux is the first method ever to measure the volume blood flow to foetuses.
To measure true flow volumes is a potential advantage over conventional RI and PI measurements in the umbilical artery. Flow volumes describe precisely which amount of blood and hands which amount of oxygen and nutrients is transported via the umbilical cord towards the foetus.
We could demonstrate that the foetal volume flow can predict foetal growth.
Foetuses which are going to develop an intrauterine growth retardation (IUGR) receive significantly less blood volume per gram fetal weight.
The clue for realistic perfusion measurement is 3D-and the correction of Doppler signals. This became feasible only by using 3-D-colour Doppler data for perfusion measurements. So far, only flow velocity changes during a heart cycle were used to get an estimate of the haemodynamic status of the foetus.
PixelFlux uses the colour Doppler signals from the umbilical vein. No matter, which shape the vein has, no matter, which direction of flow exists at the point of examination, PixelFlux reliably calculates the spatially angle-corrected flow volume pixel by pixel from your conventional 3D-colour Doppler data.
PixelFlux was also used to detect the vasomotion of the umbilical vein. This discovery was awarded with the first European Ultrasound Award in 2015.
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